Supreme Court Associate Justice David Souter announced he would be retiring at the end of the spring session. He was on the court's moderate to liberal wing in terms of his decisions. Expect President Obama to appoint a fairly liberal judge but will make the effort to be moderate with his decision. Expect a swift confirmation no matter who he chooses.
My feelings on the Supreme Court are as this. I usually do not have too many beefs with the selection as long as they are qualified to do the job. The most qualified justices will review all of the details very carefully before making a final decision on the case. There have been many instances where a conservative justice may turn out to decide more moderate or even liberal. Despite being conservatives, I have tremendous respect for Justices John Roberts and Sam Alito (although it does not help if you mess up the oath). It will be an interesting process.